HORDB

ID: hor002891
Uniprot ID: P11975
Protein name: Neuropeptide D
Gene name: NA
Organism: Cardisoma carnifex (Blue land crab)
Family: NA
Source: animal
Expression: sinus gland
Disease: NA
Comments: NA
Taxonomy: Cardisoma (genus), Gecarcinidae (family), Grapsoidea (superfamily), Thoracotremata, Eubrachyura, Brachyura (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Function: Neuropeptide H is the precursor molecule for neuropeptides C, D, E, F and I, which arise by incomplete proteolysis of neuropeptide H.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-Q62949-F1.pdb

hor002891_AF2.pdb

hor002891_ESM.pdb

Mass:	208612	Formula:	C74H117N21O29
Absent amino acids:	CDFIKMNQRTVWY	Common amino acids:	A
pI:	3.98	Basic residues:	1
Polar residues:	5	Hydrophobic residues:	8
Hydrophobicity:	-8.95	Boman Index:	-1271
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	72.63
Instability Index:	4292.11	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 3298549
Title: Amino acid sequences of neuropeptides in the sinus gland of the land crab Cardisoma carnifex: a novel neuropeptide proteolysis site.